Fish allergy-natural history and crossreactivity between fish species
نویسندگان
چکیده
Material and methods 105 children with a diagnosis of type I allergy to fish, based on history, specific IgE (sIgE, CAP) to codfish (f3) and skin prick tests (SPT) with commercial fish extracts, are included so far. All children undergo open food challenges (OFC) with canned tuna, fresh swordfish or fresh tuna in order to evaluate whether these fishes are tolerated or not by fish allergic children. Subsequently, those children showing signs of reduced clinical reactivity are subjected to double blind placebo controlled food challenges (DBPCFC) with codfish, followed by OFC to codfish in those with a negative DBPCFC, to evaluate the natural history.
منابع مشابه
Specific IgE to fish extracts does not predict allergy to specific species within an adult fish allergic population
BACKGROUND Fish is an important cause of food allergy. Studies on fish allergy are scarce and in most cases limited to serological evaluation. Our objective was to study patterns of self-reported allergy and tolerance to different commonly consumed fish species and its correlation to IgE sensitization to the same species. METHODS Thirty-eight adult fish allergic patients completed a questionn...
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